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Bucladesine calcium
Catalog NO.: CMP-003 | CAS NO.: 938448-87-4 | Brand: BIOCAXIS
Category
Nucleosides & Nucleotides, Nucleotide
Synonyms:
Cyclic AMP; cAMP; Adenosine 3',5'-cyclophosphate;
4H-Furo[3,2-d]-1,3,2-dioxaphosphorin-7-ol, 6-(6-amino-9H-purin-9-yl)tetrahydro-2-hydroxy-, 2-oxide, (4aR,6R,7R,7aS)-; cyclic
Adenosine 3',5'-monophosphate
N6,2′-O-Dibutyryladenosine 3′,5′-cyclic
monophosphate sodium salt
Bucladesine
sodium salt, Dibutyryl cAMP sodium salt, Dibutyryl cyclic-AMP sodium salt
Molecular Formula
C18H24N5O8P.1/2Ca
Molecular Weight
488.42
General description
Bucladesine
calcium salt is a membrane permeable selective activator of PKA. It is absorbed
very rapidly and almost completely when the aqueous solution is applied to the
site where the skin has been excised. Besides, it is capable of significantly
reducing the inflammatory oedema in the arachidonic acid induced ear oedema
model in mice.
Bucladesine
calcium salt (Dibutyryl-cAMP calcium salt;DC2797 calcium salt) is a cell-permeable cyclic AMP
(cAMP) analog and selectively activates cAMP dependent protein kinase (PKA) by
increasing the intracellular level of cAMP. Bucladesine
calcium salt acts as a phosphodiesterase (PDE) inhibitor.