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Guanosine 5'-diphosphate disodium
Catalog NO.: NDP-008 | CAS NO.: 7415-69-2 | Brand: BIOCAXIS
Category
Nucleosides & Nucleotides, Nucleotide
Synonyms
GDP disodium salt, Disodium 5′-GDP,
Disodium Guanosine 5′-diphosphate, 5′-GDP-Na2
Molecular Formula
C10H13N5Na2O11P2
Molecular Weight
487.16
General description
Guanosine 5'-diphosphate (GDP) disodium salt, a purine
nucleoside diphosphate, is interconverted to guanosine by the action of exonucleotidase and phosphorylation of nucleoside to
guanine. Guanosine 5'-diphosphate disodium salt activates adenosine
5'-triphosphate-sensitive K+ channel and is used to study the kinetics and
characteristics of GTPases such as those associated with G-protein coupled
receptors (GPCR). Guanosine 5'-diphosphate disodium salt is a potential iron
mobilizer, which prevents the Hepcidin (HY-P70400)-ferroportin
interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Elevated
levels of guanosine 5’-diphosphate are associated with the pathogenesis of
neurological diseases. Guanosine 5'-diphosphate disodium salt is promising for
the research of inflammation, such as anemia of inflammation (AI).