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DMT-2′-O-TBDMS-rU Phosphoramidite
Catalog NO.: RNA-PM-004 | CAS NO.: 118362-03-1 | Brand: BIOCAXIS
Category
Carbohydrates, Nucleosides & Nucleotides, RNA Phosphoramidites
Synonyms:
5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-[(1,1-dimethylethyl)dimethylsilyl]-uridine,
3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite], DMT-2′-O-TBDMS-rU
amidite
Molecular Formula
C45H61N4O9PSi
Molecular Weight
861.05
General description
RNA phosphoramidites, along with RNA CPG, and analogous to DNA synthesis support the synthesis of sequence-specific RNA oligonucleotides for RNA interference (RNAi) and can be used in target validation and other drug development techniques.Modern phosphoramidite-mediated synthesis has enabled routine high-yielding preparations of RNA oligonucleotides. High-quality RNA phosphoramidites are key to low failure rates, the high biological activity of synthesis products
Usage
Solid phase synthesis of DNA and RNA oligonucleotides in chemical or enzymatic processes.