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5-Fluorouracil

Catalog NO.: BASE-007 | CAS NO.: 51-21-8 | Brand: BIOCAXIS

Category

Nucleosides & Nucleotides, nucleobase

Synonyms:

2,4-Dihydroxy-5-fluoropyrimidine, 5-FU, 5-Fluoro-2,4(1H,3H)-pyrimidinedione

5-FU; Fluorouracil; Adrucil

Molecular Formula

C4H3FN2O2

Molecular Weight

130.08

General description

5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer. 5-Fluorouracil also inhibits HIV.

Fluorouracil (5-Fluoracil, 5-FU) is a DNA/RNA synthesis inhibitor, which interrupts nucleotide synthetic by inhibiting thymidylate synthase (TS).

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