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Adenine

Catalog NO.: BASE-002 | CAS NO.: 73-24-5 | Brand: BIOCAXIS

Category

Nucleosides & Nucleotides, nucleobase

Synonyms:

NSC 14666; NSC-14666; NSC14666; 1H-Purin-6-amine; 6-Aminopurine; 9H-Purin-6-amine; Vitamin B4; 1,6-Dihydro-6-iminopurine; 3,6-Dihydro-6-iminopurine; 3H-Purin-6-amine; 6-Amino-1H-purine; 6-Amino-3H-purine; 6-Amino-9H-purine; 9H-Adenine; Adeninimine

Molecular Formula

C5H5N5

Molecular Weight

135.13

General description

Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis.

Adenine is a purine nucleobase, synthesized from inosine monophosphate(IMP). It is a nitrogenous heterocyclic aromatic compound.

Application

Adenine has been used:

a component of green medium used for the derivation of keratinocytes from plucked hair follicles

for the serial culture of adult murine keratinocytes

as a media component for SSEA4+ limbal stromal stem cell differentiation

Biochem/physiol Actions

Adenine is a component of important biomolecules such as adenosine triphosphate (ATP), nicotinamide adenine dinucleotide (NAD) and flavin adenine dinucleotide (FAD). NAD and FAD forms the structure of DNA and RNA, and plays important role in protein synthesis. ATP is an energy source, that is essential for cellular respiration.

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