Biocaxis > Products > Purine &
Pyrimidine |
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Catalog NO.: BASE-009
| CAS NO.: 66-22-8 |
Brand: BIOCAXIS
Category
Nucleosides & Nucleotides, nucleobase
Synonyms:
2,4(1H,3H)-Pyrimidinedione, 2,4-Dihydroxypyrimidine,
2,4-Pyrimidinediol
Molecular Formula
C4H4N2O2
Molecular Weight
112.09
General description
2,4(1H,3H)-Pyrimidinedione; 2,4-Dioxopyrimidine;
2,4-Pyrimidinedione; Pirod; Pyrod;
Fluorouracil Impurity C; 1,2,3,4-Tetrahydropyrimidine-2,4-dione;
2,4-Dihydroxypyrimidine; 2,4-Pyrimidinediol; 4-Hydroxyuracil; Hybar X; NSC 3970; Lamivudine EP Impurity F
Uracil is a pyrimidine derivative and one of the four
nucleobases in the nucleic acid of RNA. Uracil is a frequently occurring DNA
base damage that results from the spontaneous or chemically induced deamination
of cytosine and is mutagenic at the level of replication. Uracil could
potentially alter transcriptional fidelity, resulting in production of mutant
proteins.
Uracil belongs to the pyrimidine nucleobase family. It is
naturally occurring and is an important and active part of RNA.
Application
Uracil has been used as a supplement in complete synthetic
medium 1×, synthetic complete glucose-based yeast media (SC), and yeast extract
with supplements (YES) media for culturing yeast cells.
Biochem/physiol Actions
Uracil and its derivatives play an integral part in
medicinal chemistry for the synthesis of cancer, viral infections, autosomal
recessive disorder, thyroid, and diabetic drugs.
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