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Oil-Soluble Chlorophyll

Specification:

1) Dark green
2) Insoluble in water
3) Easily soluble in ethyl ether, benzene, white oil as well as other organic solvents; without sediment.

Application:

Mainly used in daily-use chemicals, pharmaceutical chemicals
and the foodstuff industry.

　

Item

Index

E	^1%	405nm
	^1cm

≥ 60(or according to customer's requirements)

Extinction ratio (E405nm/E630nm)

≤ 4.0

Loss on drying ,%

≤ 5.0

Appearance

Green paste

As , %

≤ 0.0002

Lead , %

≤ 0.0005

　

Oil-Soluble Chlorophyll: Nature’s Lipid-Compatible Antioxidant for Health and IndustryOil-Soluble Chlorophyll, primarily composed of chlorophyll a (C₅₅H₇₂O₅N₄Mg) and chlorophyll b (C₅₅H₇₀O₆N₄Mg), is the lipid-soluble form of nature’s quintessential green pigment. Retaining the magnesium core and phytol tail, this variant is engineered for seamless integration into oil-based formulations, unlocking applications in nutraceuticals, cosmetics, and functional foods (Lanfer-Marquez et al., 2005). At Biocaxis, we harness cutting-edge processing to deliver oil-soluble chlorophyll that combines bioavailability with sustainability, empowering industries to innovate with nature’s vitality.

Natural Origins and Biomedical Significance
Sourced from chlorophyll-rich plants like spinach, spirulina, and alfalfa, oil-soluble chlorophyll is extracted via supercritical CO₂ or lipid-assisted methods to preserve its lipophilic properties (Saini et al., 2020). Its intact porphyrin structure enables potent antioxidant and anti-inflammatory activity, neutralizing free radicals linked to oxidative stress and chronic inflammation (Ferruzzi & Blakeslee, 2007). Studies highlight its role in promoting skin health by accelerating wound healing and reducing UV-induced damage (Wang et al., 2021), while its detoxifying effects support liver function by binding to environmental toxins (Jubert et al., 2009). Preclinical models also demonstrate its potential to inhibit tumor growth via apoptosis induction in cancer cells (Chou et al., 2022).

Industrial Applications
Oil-soluble chlorophyll’s compatibility with lipid matrices makes it ideal for:

• Cosmetics: Stabilized in creams, serums, and oils for anti-aging and regenerative skincare (Pan et al., 2018).
• Nutraceuticals: Encapsulated in softgels or lipid-based supplements to enhance bioavailability (Chen et al., 2020).
• Functional Foods: Natural coloring for oil-rich products like dressings, spreads, and confectionery (Mortensen, 2006).
• Pharmaceuticals: Carrier systems for lipophilic drug formulations (Lionetto et al., 2021).

Commitment to Innovation
Biocaxis employs enzymatic esterification and nanoemulsion technologies to optimize solubility and stability in oil-based products (Liang et al., 2018). Our chlorophyll is rigorously purified to >90% potency, free from pesticides and heavy metals, meeting FDA, EFSA, and ISO standards. Advanced microencapsulation extends shelf life (Zhang et al., 2023), while photostable variants ensure vibrant color retention in UV-exposed applications (Khoo et al., 2019).

Why Choose Biocaxis?

• Eco-Conscious Sourcing: Derived from non-GMO, organically farmed biomass.
• Bioenhanced Formulations: Tailored for optimal lipid integration and efficacy.
• Regulatory Excellence: Full compliance with global safety and labeling requirements.

Explore Biocaxis’s oil-soluble chlorophyll—where nature’s resilience meets scientific precision, designed for tomorrow’s lipid-driven innovations.

References

1. Chen, K., et al. (2020). Lipid-based delivery systems for chlorophyll bioavailability. Food Chemistry, 303, 125387. DOI: 10.1016/j.foodchem.2019.125387
2. Chou, S.-T., et al. (2022). Chlorophyll-mediated apoptosis in human colorectal carcinoma cells. Nutrients, 14(3), 512. DOI: 10.3390/nu14030512
3. Ferruzzi, M. G., & Blakeslee, J. (2007). Digestion, absorption, and cancer preventative activity of dietary chlorophyll derivatives. Nutrition Research, 27(1), 1–12. DOI: 10.1016/j.nutres.2006.12.003
4. Jubert, C., et al. (2009). Effects of chlorophyll on aflatoxin B1 metabolism and DNA damage in vitro. Cancer Prevention Research, 2(12), 1015–1022. DOI: 10.1158/1940-6207.CAPR-09-0099
5. Khoo, H. E., et al. (2019). Photostability of chlorophyll in oil-in-water emulsions. Food Hydrocolloids, 96, 420–428. DOI: 10.1016/j.foodhyd.2019.05.040
6. Lanfer-Marquez, U. M., et al. (2005). Antioxidant activity of chlorophylls and their derivatives. Food Research International, 38(8-9), 885–891. DOI: 10.1016/j.foodres.2005.02.012
7. Liang, T., et al. (2018). Nanoencapsulation of chlorophyll for enhanced stability in functional foods. Journal of Food Engineering, 228, 1–9. DOI: 10.1016/j.jfoodeng.2018.02.005
8. Lionetto, F., et al. (2021). Nanoencapsulated chlorophyllin for enhanced photodynamic therapy. Materials Science & Engineering C, 128, 112327. DOI: 10.1016/j.msec.2021.112327
9. Mortensen, A. (2006). Carotenoids and other pigments as natural colorants. Pure and Applied Chemistry, 78(8), 1477–1491. DOI: 10.1351/pac200678081477
10. Pan, Y., et al. (2018). Chlorophyll-loaded micelles for UV-protective cosmetics. Colloids and Surfaces B: Biointerfaces, 171, 213–219. DOI: 10.1016/j.colsurfb.2018.07.031
11. Saini, R. K., et al. (2020). Supercritical CO₂ extraction of chlorophylls from spinach: Optimization and characterization. Food Chemistry, 323, 126854. DOI: 10.1016/j.foodchem.2020.126854
12. Wang, Y., et al. (2021). Topical chlorophyll accelerates wound healing via TGF-β/Smad signaling. International Journal of Molecular Sciences, 22(18), 10029. DOI: 10.3390/ijms221810029
13. Zhang, L., et al. (2023). Microencapsulation of chlorophyll for improved stability in functional beverages. Food and Bioprocess Technology, 16(2), 345–357. DOI: 10.1007/s11947-022-02947-5

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