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Biocaxis > Products > chlorophyllin

Pheophorbide

Specification:

       Molecular Formula: C₃₅H₃₆N₄O₅

       CAS Number: 24533-72-0 (Pheophorbide a)

       Storage: Stable at -20<C, protected from light.

       Solubility: Soluble in organic solvents (e.g., DMSO, ethanol) and aqueous solutions at neutral to alkaline pH.

Application:

Key Applications

           Photodynamic Therapy (PDT).

           Bioimaging.

           Antimicrobial Research.

           Photosynthesis Studies.

 


 

Pheophorbide

Specifications

       Molecular Formula: C₃₅H₃₆N₄O₅

       CAS Number: 24533-72-0 (Pheophorbide a)

       Storage: Stable at -20<C, protected from light.

       Solubility: Soluble in organic solvents (e.g., DMSO, ethanol) and aqueous solutions at neutral to alkaline pH.

Pheophorbide is a chlorophyll-derived porphyrin compound formed by the removal of magnesium and phytol groups from chlorophyll. This chlorin structure gives it unique photochemical properties, making it a valuable tool in biomedical research and therapeutic applications. Available as a high-purity powder or customized formulations, Pheophorbide is widely used for its photosensitizing capabilities and versatile functionality.

Key Applications

       Photodynamic Therapy (PDT): Pheophorbide acts as a potent photosensitizer. Upon light activation, it generates reactive oxygen species (ROS) to selectively destroy cancer cells or pathogens. Studies highlight its efficacy in targeting tumors while minimizing damage to healthy tissues.

       Bioimaging: Its inherent fluorescence enables non-invasive tracking of cellular processes, aiding in cancer diagnostics and drug delivery studies.

       Antimicrobial Research: Demonstrates activity against drug-resistant bacteria and fungi under light exposure, offering promise for treating infections.

       Photosynthesis Studies: Used to investigate chlorophyll degradation pathways and plant stress responses.

Production & Quality
Pheophorbide is typically extracted from natural chlorophyll sources (e.g., spinach, algae) or synthesized via demetallation of chlorophyll derivatives. Rigorous purification ensures >95% purity, validated by HPLC and NMR. The product is offered in lyophilized powder form, with options for solubilization in DMSO or aqueous buffers (pH-dependent).

Safety & Handling
Handle under subdued lighting to prevent premature activation. Use personal protective equipment (PPE) to avoid skin/eye exposure.  

Future Potential
Ongoing studies explore Pheophorbide¨s role in combination therapies and nanotechnology-based drug delivery. Its natural origin and adaptability position it as a sustainable choice for advancing precision medicine.

 

 

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