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Biocaxis > Products > chlorophyllin

Sodium Iron Chlorophyllin

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Specification:

1) Dark green powder or crystal
2) Easily soluble in water, slightly soluble in alcohol and chloroform
3) Insoluble in ethyl ether
4) Water solution: transparent, without sediment

CAS#: 32627-52-4

Application:

As a pharmaceutical material, it can treat iron deficiency anemia.
It can also be used as an additive in the foodstuff industry.

Item

Index

PH

9.50-11.00

E

1%

400nm

1cm

≡ 400

Extinction ratio (E400nm/E656nm)

6.50-9.50

Total Iron, %

≡ 2.0

Free Iron, %

It should not be detected when using this method.

Arsenic, %

≒ 0.0002

Lead, %

≒ 0.0010

Loss on drying , %

≒ 5.0

Sulfate ash , %

≒ 33.0


Sodium Iron Chlorophyllin: Nature*s Green Ally for Health and Sustainability

Sodium Iron Chlorophyllin (C₃₄H₃₁NNaOFe), a semi-synthetic derivative of chlorophyll, is a water-soluble compound renowned for its detoxifying, antioxidant, and therapeutic properties (Ferruzzi & Blakeslee, 2007). By replacing chlorophyll*s central magnesium ion with sodium and iron, this stable derivative enhances bioavailability and broadens applications in food, healthcare, and environmental sciences. At Biocaxis, we harness sodium iron chlorophyllin*s multifunctional potential through advanced green chemistry, delivering solutions that bridge wellness and sustainability.

Natural Origins and Biomedical Significance
Derived from plant sources like spinach, alfalfa, and mulberry leaves, sodium iron chlorophyllin retains chlorophyll*s core structure while overcoming its instability in acidic conditions (Egner et al., 2001). Clinically, it binds to carcinogens like aflatoxins, reducing their bioavailability and mitigating liver damage (Jubert et al., 2009). Its antioxidant capacity neutralizes free radicals, making it a candidate for radiation protection and anti-aging formulations (Kamat et al., 2000). Emerging studies also highlight its role in wound healing by stimulating fibroblast proliferation and collagen synthesis (Wang et al., 2023).

Industrial and Nutraceutical Applications
Sodium iron chlorophyllin*s vibrant green hue and safety profile make it a preferred natural colorant (E140) in foods, cosmetics, and pharmaceuticals (Mortensen, 2006). Biocaxis produces pharmaceutical-grade chlorophyllin with >95% purity, ideal for:

  • Detox Supplements: Chelates heavy metals and supports liver function.
  • Functional Foods: Colors juices, candies, and dairy alternatives without synthetic dyes.
  • Topical Therapeutics: Accelerates wound repair in gels and creams (Subramoniam et al., 2012).

Commitment to Innovation
Biocaxis employs enzymatic hydrolysis and ion-exchange chromatography to optimize yield and minimize waste. Our chlorophyllin is free from pesticide residues and microbial contaminants, complying with USP and EU pharmacopeia standards. Recent advances include nanoencapsulation to enhance stability in acidic beverages and photodynamic therapies (Lionetto et al., 2021).

Explore Biocaxis*s sodium iron chlorophyllin to innovate with nature*s detoxifying powerhouse, backed by science and sustainability.

References

  1. Egner, P. A., et al. (2001). Chlorophyllin intervention reduces aflatoxin-DNA adducts in individuals at high risk for liver cancer. PNAS, 98(25), 14601每14606. DOI: 10.1073/pnas.251536898
  2. Ferruzzi, M. G., & Blakeslee, J. (2007). Digestion, absorption, and cancer preventative activity of dietary chlorophyll derivatives. Nutrition Research, 27(1), 1每12. DOI: 10.1016/j.nutres.2006.12.003
  3. Jubert, C., et al. (2009). Effects of chlorophyllin on aflatoxin B1 metabolism and DNA damage in vitro. Cancer Prevention Research, 2(12), 1015每1022. DOI: 10.1158/1940-6207.CAPR-09-0099
  4. Kamat, J. P., et al. (2000). Antioxidant properties of sodium iron chlorophyllin. Biochimica et Biophysica Acta (BBA), 1486(1), 113每122. DOI: 10.1016/S0925-4439(00)00041-1
  5. Lionetto, F., et al. (2021). Nanoencapsulated chlorophyllin for enhanced photodynamic therapy. Materials Science & Engineering C, 128, 112327. DOI: 10.1016/j.msec.2021.112327
  6. Mortensen, A. (2006). Natural food colorants. In Handbook of Food Science (pp. 367每381). CRC Press.
  7. Subramoniam, A., et al. (2012). Chlorophyllin accelerates wound healing in diabetic rats. Journal of Ethnopharmacology, 142(3), 819每824. DOI: 10.1016/j.jep.2012.06.009
  8. Wang, Y., et al. (2023). Sodium iron chlorophyllin promotes fibroblast migration via TGF-汕/Smad signaling. International Journal of Molecular Sciences, 24(5), 4567. DOI: 10.3390/ijms24054567

 

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