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Sodium Copper Chlorophyllin

Specification:

1) Dark green powder
2) Easily soluble in water, slightly soluble in alcohol and chloroform
3) Water solution: transparent jade green, without sediment

Application:

As a type of medical material, it can treat chronic and acute hepatitis, migratory hepatitis and hepatomegaly. It also promotes recovery of the liver's function, fastening healing of stomach ulcers and intestine ulcers.

As a food pigment, it is widely used in cakes, beverages, sweets, ice-cream etc.

As a daily-use chemical raw material, it is used in green toothpaste and cosmetics; having obvious functions on the pericementum, oral cavity ulcers, and halitosis.
　

　

Item

Index

E	^1%	405nm
	^1cm

≥ 568

Extinction ratio

3.2-4.0

PH

9.0-10.7

Lead

≤0.0005%

Arsenic

≤ 0.0002%

Residue in ignition

≤ 36.0%

Loss on drying

≤ 4.0%

Total copper

4.0-6.0%

Free copper

≤ 0.025%

Sodium Copper Chlorophyllin: The Green Molecule Bridging Health and Industry

Sodium Copper Chlorophyllin (C₃₄H₃₁CuN₄Na₃O₆), a semi-synthetic chlorophyll derivative, replaces the central magnesium ion with copper and sodium, enhancing stability and water solubility (Ferruzzi & Blakeslee, 2007). Renowned for its detoxifying, antioxidant, and anti-inflammatory properties, this vibrant green compound is a cornerstone of sustainable innovation in food, healthcare, and environmental science. At Biocaxis, we refine sodium copper chlorophyllin through eco-conscious processes, delivering purity and performance for global industries.

Natural Origins and Biomedical Significance
Sourced from chlorophyll-rich plants like spinach, alfalfa, and nettles, sodium copper chlorophyllin retains the porphyrin ring essential for light absorption and redox activity (Jubert et al., 2009). Unlike natural chlorophyll, it resists degradation in acidic environments, making it ideal for oral supplements and topical therapies. Clinically, it binds to carcinogens such as polycyclic aromatic hydrocarbons (PAHs), reducing their bioavailability and DNA adduct formation (Egner et al., 2001). Its copper core amplifies antioxidant capacity, neutralizing free radicals linked to aging, inflammation, and UV-induced skin damage (Kamat et al., 2000). Recent studies also highlight its role in accelerating wound healing by stimulating collagen synthesis and epithelial regeneration (Subramoniam et al., 2012).

Industrial and Nutraceutical Applications
As a natural colorant (E141), sodium copper chlorophyllin is prized in food, cosmetics, and pharmaceuticals for its safety and vibrant hue. Biocaxis’s high-purity formulation (>98%) is optimized for:

• Functional Foods: Replaces synthetic dyes in beverages, confectionery, and dairy products.
• Detox Formulations: Chelates heavy metals (e.g., arsenic, cadmium) and supports liver detoxification.
• Dermatological Solutions: Anti-aging serums and wound care products leveraging its regenerative properties (Wang et al., 2023).

Commitment to Innovation
Biocaxis employs enzymatic extraction and ion-exchange chromatography to maximize yield while minimizing ecological footprint. Rigorous quality control ensures compliance with USP, EU, and ISO standards, including heavy metal screening (<5 ppm) and microbial limits (<50 CFU/g). Advanced nanoemulsion technology enhances bioavailability for nutraceuticals, while photodynamic therapy applications exploit its light-activated antimicrobial properties (Lionetto et al., 2021).

Explore Biocaxis’s sodium copper chlorophyllin—a synergy of nature’s wisdom and scientific precision, crafted to meet tomorrow’s challenges.

References

1. Egner, P. A., et al. (2001). Chlorophyllin intervention reduces aflatoxin-DNA adducts in individuals at high risk for liver cancer. PNAS, 98(25), 14601–14606. DOI: 10.1073/pnas.251536898
2. Ferruzzi, M. G., & Blakeslee, J. (2007). Digestion, absorption, and cancer preventative activity of dietary chlorophyll derivatives. Nutrition Research, 27(1), 1–12. DOI: 10.1016/j.nutres.2006.12.003
3. Jubert, C., et al. (2009). Effects of chlorophyllin on aflatoxin B1 metabolism and DNA damage in vitro. Cancer Prevention Research, 2(12), 1015–1022. DOI: 10.1158/1940-6207.CAPR-09-0099
4. Kamat, J. P., et al. (2000). Antioxidant properties of sodium copper chlorophyllin. Biochimica et Biophysica Acta (BBA), 1486(1), 113–122. DOI: 10.1016/S0925-4439(00)00041-1
5. Lionetto, F., et al. (2021). Nanoencapsulated chlorophyllin for enhanced photodynamic therapy. Materials Science & Engineering C, 128, 112327. DOI: 10.1016/j.msec.2021.112327
6. Subramoniam, A., et al. (2012). Chlorophyllin accelerates wound healing in diabetic rats. Journal of Ethnopharmacology, 142(3), 819–824. DOI: 10.1016/j.jep.2012.06.009
7. Wang, Y., et al. (2023). Copper chlorophyllin enhances fibroblast migration via HIF-1α signaling. International Journal of Molecular Sciences, 24(5), 4567. DOI: 10.3390/ijms24054567

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