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2′-Deoxy-2′-fluoroadenosine Chemical Structure 2′-Deoxy-2′-fluoroguanosine

Catalog NO.: F-M-003 | CAS NO.: 78842-13-4 | Brand: BIOCAXIS

Category

Nucleosides & Nucleotides, 2’-modified

Synonyms:

 2'-F-2'-dG

2-amino-9-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-ol

Molecular Formula

C10H12FN5O4

Molecular Weight

285.23

General description

2′-Deoxy-2′-fluoroguanosine, a nucleoside analog, is a potent inhibitor of influenza virus strains, with an EC90 of <0.35 μM for influenza virus A and B strains. 2′-Deoxy-2′-fluoroguanosine significantly inhibits replication of influenza virus in the upper respiratory tract, resulting in amelioration of fever and nasal inflammation.

 

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