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L-Uridine
Catalog NO.: L-NS-004
| CAS NO.: 26287-69-4 | Brand: BIOCAXIS
Category
Nucleosides & Nucleotides, L-nucleoside
Synonyms:
1-(b-L-ribofuranosyl) uracil
Molecular Formula
C9H12N2O6
Molecular Weight
244.20
General description
L-Uridine is a nucleoside that is the major precursor of
RNA and DNA. It is also an equilibrative nucleoside, which
means that it can act as either an acid or a base. L-Uridine has been shown to
have anti-tumor activity in squamous cell carcinoma and human malignancies. It
has also been shown to be an active inhibitor of arabinoside, which is a drug
used for the treatment of acute myeloid leukemia (AML). L-Uridine may also have
antitumor immunity effects by activating natural killer cells.
L-Uridine, isolated from the Polyporaceae
fungus Poria cocos (Schw.), is an enantiomer of the
normal RNA constituent D-uridine. L-uridine acts as a phosphate acceptor for
nucleoside phosphotransferases.